Routine upper gastro-intestinal tract endoscopy before elective cholecystectomy for symptomatic gallstones-justified

dc.contributor.authorMorrison, Sherwyn
dc.contributor.authorMokoena, Taole
dc.contributor.emailtaole.mokoena@up.ac.za
dc.date.accessioned2025-07-23T11:45:04Z
dc.date.available2025-07-23T11:45:04Z
dc.date.issued2024-06-18
dc.descriptionDATA AVAILABILITY : Data is available from the corresponding author on reasonable request.
dc.description.abstractGallstones are common in Western countries and increasing in developing countries through adoption of western lifestyle. Gallstones may cause life-threatening complications, including acute cholecystitis, acute cholangitis, and acute pancreatitis. Cholecystectomy is the treatment of choice for symptomatic gallstones. Presentation of symptomatic gallstones may be indistinguishable from that of other upper gastro-intestinal tract (UGI) pathologies. Some surgeons routinely perform preoperative UGI endoscopy to diagnose and treat concomitant UGI pathology. A prospective cross-sectional observational study was undertaken at University of Pretoria teaching hospitals to evaluate this practice. Patients aged 18 years and older, with symptomatic gallstones but did not satisfy Tokyo guidelines for acute cholecystitis were recruited. UGI endoscopy was performed before cholecystectomy. There were 124 patients, 110 (88.7%) females and 14 (11.3%) males, mean age 44.0 (13.2) (range: 22–78) years. Most common symptoms were right upper quadrant (RUQ) pain (87%), epigastric pain (59.7%), nausea (58.1%) and vomiting (47.9%). Clinically, 80% had RUQ tenderness and 52.4% epigastric tenderness. UGI endoscopy found 35.4% pathology, 28.2% were active, and comprised acute gastritis (27.4%), peptic ulcers (4.8%), duodenitis (3.2%) and oesophagitis (2.4%). Twelve patients had more than one pathology. This warranted treatment before elective cholecystectomy and justifies the practice of routine preoperative UGI endoscopy.
dc.description.departmentSurgery
dc.description.librarianam2025
dc.description.sdgSDG-03: Good health and well-being
dc.description.sponsorshipInternal resources of the Department of Surgery.
dc.description.urihttps://www.nature.com/srep/
dc.identifier.citationMorrison, S. & Mokoena, T. 2024, 'Routine upper gastro‑intestinal tract endoscopy before elective cholecystectomy for symptomatic gallstones‑justified', Scientific Reports, vol. 14, art. 14042, pp. 1-4. https://doi.org/10.1038/s41598-024-64019-2.
dc.identifier.issn2045-2322 (online)
dc.identifier.other10.1038/s41598-024-64019-2
dc.identifier.urihttp://hdl.handle.net/2263/103553
dc.language.isoen
dc.publisherNature Research
dc.rights© 2024. The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License.
dc.subjectGallstones
dc.subjectRoutine
dc.subjectUpper gastro-intestinal endoscopy
dc.subjectCholecystectomy
dc.subjectUpper gastro-intestinal (UGI)
dc.titleRoutine upper gastro-intestinal tract endoscopy before elective cholecystectomy for symptomatic gallstones-justified
dc.typeArticle

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