Etorphine induces pathophysiology in immobilized white rhinoceros through sympathomimesis that is attenuated by butorphanol
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Publisher
Oxford University Press
Abstract
Please read abstract in the article.
LAY SUMMARY
White rhinoceros are a sentinel species for ecosystems in southern Africa. Their conservation is dependent on occasional immobilization with the ultra-potent opioid etorphine. Unfortunately, etorphine produces sympathetic nervous system upregulation and severe physiological perturbations that may cause morbidity and mortality. Attenuating its effects contributes to white rhinoceros conservation.
Description
DATA AVAILABILITY : All relevant data and resources can be found within the article and its supplementary information.
Keywords
Butorphanol, Ceratotherium simum, White rhinoceros (Ceratotherium simum), Etorphine, Hypoxaemia, Noradrenaline, Sympathetic, Conservation
Sustainable Development Goals
SDG-03: Good health and well-being
SDG-15: Life on land
SDG-15: Life on land
Citation
Jordyn M. Boesch, Robin D. Gleed, Peter E. Buss, Adrian S.W. Tordiffe, Gareth E. Zeiler, Michele A. Miller, Francois Viljoen, Brian H. Harvey, Stephen A. Parry, Leith C.R. Meyer, Etorphine induces pathophysiology in immobilized white rhinoceros through sympathomimesis that is attenuated by butorphanol, Conservation Physiology, Volume 13, Issue 1, 2025, coaf009, pp. 1-21, https://doi.org/10.1093/conphys/coaf009.